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Article

Haplotypic association spanning the 22q11.21 genes COMT and ARVCF with schizophrenia.

Molecular psychiatry - 1 Apr 2005

Sanders A R, Rusu I, Duan J, Vander Molen J E, Hou C, Schwab S G, Wildenauer D B, Martinez M, Gejman P V

Abstract excerpt

Catechol-O-methyltransferase (COMT) has been implicated in schizophrenia by its function through its roles in monoamine neurotransmitter metabolism and its impact on prefrontal cognition, and also by its position through linkage scans and a strong cytogenetic association. Further support comes fr...

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Source

Identifiers

PMID: 15340358
DOI: 10.1038/sj.mp.4001586

Genes

ARVCF
COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15340358-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Haplotypic association spanning the 22q11.21 genes COMT and ARVCF with schizophrenia.PMID 15340358Read ↗

ARVCF single marker and haplotypic association with schizophrenia.Semantic proximity Read ↗

Association analysis of COMT polymorphisms and schizophrenia in a Chinese Han population: a case-control study.Semantic proximity Read ↗

A highly significant association between a COMT haplotype and schizophrenia.Semantic proximity Read ↗

Association of the 3' region of COMT with schizophrenia in Taiwan.Semantic proximity Read ↗

Separate and interacting effects within the catechol-O-methyltransferase (COMT) are associated with schizophrenia.Semantic proximity Read ↗

Variants in the catechol-o-methyltransferase (COMT) gene are associated with schizophrenia in Irish high-density families.Semantic proximity Read ↗

Association of the low-activity COMT 158Met allele with ADHD and OCD in subjects with velocardiofacial syndrome.Semantic proximity Read ↗

A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain.Semantic proximity Read ↗

Genetic variants in COMT and neurocognitive impairment in families of patients with schizophrenia.Semantic proximity Read ↗

Meta-analysis of association between genetic variants in COMT and schizophrenia: an update.Semantic proximity Read ↗

A family based study of catechol-O-methyltransferase (COMT) and attention deficit hyperactivity disorder (ADHD).Semantic proximity Read ↗

Association between Val108/158 Met polymorphism of the COMT gene and schizophrenia.Semantic proximity Read ↗

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