Article
Immunogenetic features in 120 Japanese patients with idiopathic inflammatory myopathy.
The Journal of rheumatology - 1 Sept 2004
Furuya Takefumi, Hakoda Masayuki, Tsuchiya Naoyuki, Kotake Shigeru, Ichikawa Naomi, Nanke Yuki, Nakajima Ayako, Takeuchi Megumi, Nishinarita Makoto, Kondo Hirobumi, Kawasaki Aya, Kobayashi Shio, Mimori Tsuneyo, Tokunaga Katsushi, Kamatani Naoyuki
Abstract excerpt
OBJECTIVE: To examine the role of HLA-DRB1 and tumor necrosis factor (TNF) promoter genotypes in the development and the autoantibody profiles of idiopathic inflammatory myopathy (IIM) in Japanese patients. METHODS: HLA-DRB1 and TNF promoter genotypes were determined, and serum antinuclear autoantibodies were identified in 120 adult Japanese patients with IIM [72 with dermatomyositis (DM), 30 with polymyositis...
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