Article
HLA class II haplotypes associated with pulmonary interstitial lesions of polymyositis/dermatomyositis in Japanese patients.
Tissue antigens - 1 Jan 2002
Horiki T, Ichikawa Y, Moriuchi J, Hoshina Y, Yamada C, Wakabayashi T, Jackson K, Inoko H
Abstract excerpt
To elucidate the immunogenetic background of idiopathic inflammatory myopathies (IIM) such as polymyositis (PM), dermatomyositis (DM) and any overlapping subsets, with other collagen vascular diseases, HLA class I antigens and class II alleles were determined and compared from individuals with various clinical and serological features of IIM, including pulmonary interstitial lesions (PI). Seventy-three Japanese...
Topics
- Adolescent
- Aged
- Alleles
- Dermatomyositis
- Female
- Gene Frequency
- Genes, MHC Class II
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- HLA-DR Antigens
- HLA-DRB1 Chains
- Haplotypes
- Histocompatibility Antigens Class II