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Article

Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis.

RNA (New York, N.Y.) - 1 Oct 2004

Pillai Ramesh S, Artus Caroline G, Filipowicz Witold

Abstract excerpt

MicroRNAs (miRNAs) are approximately 21-nt-long RNAs involved in regulating development, differentiation, and other processes in eukaryotes. In metazoa, nearly all miRNAs control gene expression by imperfectly base-pairing with the 3'-untranslated region (3'-UTR) of target mRNAs and repressing protein synthesis by an unknown mechanism. It is also unknown whether miRNA-mRNA duplexes containing mismatches and...

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Identifiers

PMID: 15337849
DOI: 10.1261/rna.7131604
PMCID: PMC1370638

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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