Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A follow-up linkage study for bone size variation in an extended sample.

Bone - 1 Sept 2004

Xu Fu-Hua, Liu Yong-Jun, Deng Hongyi, Huang Qing-Yang, Zhao Lan-Juan, Shen Hui, Liu Yao-Zhong, Dvornyk Volodymyr, Conway Theresa, Li Jin-Long, Davies K Michael, Recker Robert R, Deng Hong-Wen

Abstract excerpt

Bone size, which has strong genetic determination, is an important determinant of bone strength and a risk factor of osteoporotic fractures. We previously reported an approximately 10-cm genome-wide linkage scan in 630 subjects from 53 US Caucasian pedigrees. The strongest evidence of linkage was obtained on chromosome 17q22 near the marker D17S787, with a two-point LOD score of 3.98 and a multipoint maximum LOD...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone and Bones
Share to Bone Density

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bone Development

Share to Chromosomes, Human, Pair 17

Share to Follow-Up Studies

Share to Genetic Linkage

Share to Lod Score

Share to Quantitative Trait Loci

Source

Identifiers

PMID: 15336616
DOI: 10.1016/j.bone.2004.05.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A follow-up linkage study for bone size variation in an extended sample.PMID 15336616Read ↗

A genome-wide linkage scan for bone mineral density in an extended sample: evidence for linkage on 11q23 and Xq27.Semantic proximity Read ↗

A bivariate whole genome linkage study identified genomic regions influencing both BMD and bone structure.Semantic proximity Read ↗

Linkage exclusion mapping with bone size in 79 Caucasian pedigrees.Semantic proximity Read ↗

Genome-Wide Linkage Screen of Bone Mineral Density (BMD) in European Pedigrees Ascertained through a Male Relative with Low BMD Values: Evidence for Quantitative Trait Loci on 17q21–23, 11q12–13, 13q12–14, and 22q11Semantic proximity Read ↗

Pleiotropic loci underlying bone mineral density and bone size identified by a bivariate genome-wide association analysis.Semantic proximity Read ↗

Genome scan for QTLs underlying bone size variation at 10 refined skeletal sites: genetic heterogeneity and the significance of phenotype refinement.Semantic proximity Read ↗

A follow-up association study of two genetic variants for bone mineral density variation in Caucasians.Semantic proximity Read ↗

A second-stage genome scan for QTLs influencing BMD variation.Semantic proximity Read ↗

Genome-wide linkage scan for maximum and length-dependent knee muscle strength in young men: significant evidence for linkage at chromosome 14q24.3.Semantic proximity Read ↗

Genome screen for quantitative trait loci contributing to normal variation in bone mineral density: the Framingham Study.Semantic proximity Read ↗

Refined QTLs of osteoporosis-related traits by linkage analysis with genome-wide SNPs: Framingham SHARe.Semantic proximity Read ↗

Linkage and association analyses using families identified a locus affecting an osteoporosis-related trait.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.