Article
Allelic polymorphisms in the FcgammaRIIC gene can influence its function on normal human natural killer cells.
Journal of molecular medicine (Berlin, Germany) - 1 Apr 2002
Ernst Linda K, Metes Diana, Herberman Ronald B, Morel Penelope A
Abstract excerpt
Natural killer (NK) cells are important in host defense against viruses and tumors and can induce death of virally infected cells following engagement of cell surface receptors. Human NK cells express receptors for the Fc portion of IgG which stimulate antibody-dependent cell-mediated cytotoxicity and induce cytokine production. We have shown that NK cells from certain individuals can express, in addition to CD16...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
