Article
[Protective role of HLA-B27 in HIV and hepatitis C virus infection].
Deutsche medizinische Wochenschrift (1946) - 1 Feb 2011
Neumann-Haefelin C
Abstract excerpt
The human leukocyte antigen (HLA) B27 has been linked to rheumatic diseases such as ankylosing spondylitis nearly 40 years ago, but its role in pathogenesis remains unclear. Apart from this association, HLA-B27 has a positive effect in two of the most threatening human viral infections: in HIV infection, HLA-B27 positive patients have low viral loads, CD4+ T cell counts decline slowly and AIDS progresses slowly....
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