Article
MHC-driven HIV-1 control on the long run is not systematically determined at early times post-HIV-1 infection.
AIDS (London, England) - 17 Jul 2013
Antoni Guillemette, Guergnon Julien, Meaudre Céline, Samri Assia, Boufassa Faroudy, Goujard Cécile, Lambotte Olivier, Autran Brigitte, Rouzioux Christine, Costagliola Dominique, Meyer Laurence, Theodorou Ioannis
Abstract excerpt
INTRODUCTION: Human leukocyte antigen (HLA) class I-driven long-term protection against HIV-1 is mainly associated with HLA-B*27 and HLA-B*57. This effect is observed early after infection. Clarification needs to be established concerning the moment of action for the other HLA-B or HLA-C alleles. METHODS: HLA-B and HLA-C alleles from 111 individuals that control HIV-1 disease for over 8 years and from 747...
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