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Article

NSs protein of Rift Valley fever virus blocks interferon production by inhibiting host gene transcription.

Journal of virology - 1 Sept 2004

Billecocq Agnès, Spiegel Martin, Vialat Pierre, Kohl Alain, Weber Friedemann, Bouloy Michèle, Haller Otto

Abstract excerpt

Rift Valley fever virus (RVFV) is an important cause of epizootics and epidemics in Africa and a potential agent of bioterrorism. A better understanding of the factors that govern RVFV virulence and pathogenicity is required, given the urgent need for antiviral therapies and safe vaccines. We have previously shown that RVFV strains with mutations in the NSs gene are excellent inducers of alpha/beta interferon...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression

Share to Interferon Type I

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Source

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Identifiers

PMID: 15331713
DOI: 10.1128/JVI.78.18.9798-9806.2004
PMCID: PMC514997

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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