Article
NSs protein of rift valley fever virus induces the specific degradation of the double-stranded RNA-dependent protein kinase.
Journal of virology - 1 May 2009
Habjan Matthias, Pichlmair Andreas, Elliott Richard M, Overby Anna K, Glatter Timo, Gstaiger Matthias, Superti-Furga Giulio, Unger Hermann, Weber Friedemann
Abstract excerpt
Rift Valley fever virus (RVFV) continues to cause large outbreaks of acute febrile and often fatal illness among humans and domesticated animals in Africa, Saudi Arabia, and Yemen. The high pathogenicity of this bunyavirus is mainly due to the viral protein NSs, which was shown to prevent transcr...
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