Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Toscana virus induces interferon although its NSs protein reveals antagonistic activity

22 Sept 2010

Abstract excerpt

Toscana virus (TOSV) is a phlebotomus-transmitted virus that belongs to the family Bunyaviridae and causes widespread infections in humans; about 30 % of these cases result in aseptic meningitis. In the present study, it was shown that TOSV is an inducer of beta interferon (IFN-β), although its non-structural protein (NSs) could inhibit the induction of IFN-β if expressed in a heterologous context. A recombinant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Eosinophilic Disorders and Syndromes
Share to Parvovirus B19 Infection Studies
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20861320
DOI: 10.1099/vir.0.025999-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Toscana virus induces interferon although its NSs protein reveals antagonistic activityPMID 20861320Read ↗

Toscana Virus NSs Protein Inhibits the Induction of Type I Interferon by Interacting with RIG-ISemantic proximity Read ↗

Novel Toscana Virus Reverse Genetics System Establishes NSs as an Antagonist of Type I Interferon Responses.Semantic proximity Read ↗

Toscana Virus NSs Protein Promotes Degradation of Double-Stranded RNA-Dependent Protein KinaseSemantic proximity Read ↗

Inhibition of interferon I induction by non-structural protein NSs of Puumala virus and other vole-associated orthohantaviruses: phenotypic plasticity of the protein and potential functional domains.Semantic proximity Read ↗

NSs protein of Rift Valley fever virus blocks interferon production by inhibiting host gene transcription.Semantic proximity Read ↗

Two strains of Toscana virus show different virulence and replication capacity in mice and cell culture modelsSemantic proximity Read ↗

Bunyamwera Bunyavirus Nonstructural Protein NSs Counteracts the Induction of Alpha/Beta InterferonSemantic proximity Read ↗

NSs Protein of Sandfly Fever Sicilian Phlebovirus Counteracts Interferon (IFN) Induction by Masking the DNA-Binding Domain of IFN Regulatory Factor 3Semantic proximity Read ↗

Characterization of the non-structural (NSs) protein of tick-borne phlebovirusesSemantic proximity Read ↗

Mapping of Transcription Termination within the S Segment of SFTS Phlebovirus Facilitated Generation of NSs Deletant VirusesSemantic proximity Read ↗

A Shared Transcription Termination Signal on Negative and Ambisense RNA Genome Segments of Rift Valley Fever, Sandfly Fever Sicilian, and Toscana VirusesSemantic proximity Read ↗

Severe Acute Respiratory Syndrome Coronavirus Open Reading Frame (ORF) 3b, ORF 6, and Nucleocapsid Proteins Function as Interferon AntagonistsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.