Article
Combined analysis of expression data and transcription factor binding sites in the yeast genome.
BMC genomics - 26 Aug 2004
Nagaraj Vijayalakshmi H, O'Flanagan Ruadhan A, Bruning Adrian R, Mathias Jonathan R, Vershon Andrew K, Sengupta Anirvan M
Abstract excerpt
BACKGROUND: The analysis of gene expression using DNA microarrays provides genome wide profiles of the genes controlled by the presence or absence of a specific transcription factor. However, the question arises of whether a change in the level of transcription of a specific gene is caused by the transcription factor acting directly at the promoter of the gene or through regulation of other transcription factors...
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