Article
From co-expression to co-regulation: how many microarray experiments do we need?
Genome biology - 1 Jan 2004
Yeung Ka Yee, Medvedovic Mario, Bumgarner Roger E
Abstract excerpt
BACKGROUND: Cluster analysis is often used to infer regulatory modules or biological function by associating unknown genes with other genes that have similar expression patterns and known regulatory elements or functions. However, clustering results may not have any biological relevance. RESULTS: We applied various clustering algorithms to microarray datasets with different sizes, and we evaluated the clustering...
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