Article

Mapping Transcription Factor Networks By Comparing Tf Binding Locations To Tf Perturbation Responses

2019-05-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> A transcription-factor (TF) network map indicates the direct, functional targets of each TF -- the genes it regulates by binding to their cis-regulatory DNA. Data on the genomic binding locations of each TF and the transcriptional responses to perturbations of its activity, such as overexpressing it, could support TF network mapping. Systematic data sets of both types exist...

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Literature Corpus work: 4536e7fa-e898-5ff1-8ff4-c8da1fcbec43
DOI: 10.1101/619676

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