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Article

Comprehensive reanalysis of transcription factor knockout expression data in Saccharomyces cerevisiae reveals many new targets.

Nucleic acids research - 1 Aug 2010

Reimand Jüri, Vaquerizas Juan M, Todd Annabel E, Vilo Jaak, Luscombe Nicholas M

Abstract excerpt

Transcription factor (TF) perturbation experiments give valuable insights into gene regulation. Genome-scale evidence from microarray measurements may be used to identify regulatory interactions between TFs and targets. Recently, Hu and colleagues published a comprehensive study covering 269 TF knockout mutants for the yeast Saccharomyces cerevisiae. However, the information that can be extracted from this...

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Source

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Identifiers

PMID: 20385592
DOI: 10.1093/nar/gkq232
PMCID: PMC2919724

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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