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Article

Protein-protein interactions in the membrane: sequence, structural, and biological motifs.

Structure (London, England : 1993) - 1 Jul 2008

Moore David T, Berger Bryan W, DeGrado William F

Abstract excerpt

Single-span transmembrane (TM) helices have structural and functional roles well beyond serving as mere anchors to tether water-soluble domains in the vicinity of the membrane. They frequently direct the assembly of protein complexes and mediate signal transduction in ways analogous to small modular domains in water-soluble proteins. This review highlights different sequence and structural motifs that direct TM...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18611372
DOI: 10.1016/j.str.2008.05.007
PMCID: PMC3771515

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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