Article
Platelet activating factor, an endogenous mediator of inflammation, induces phenotypic transformation of rat embryo cells.
Carcinogenesis - 1 Jul 1993
Bennett S A, Leite L C, Birnboim H C
Abstract excerpt
The ability of platelet activating factor (PAF), a potent endogenous inflammatory agent, to induce phenotypic transformation of primary rat embryo cells (RECs) was investigated. RECs are composed predominantly of fibroblasts, with some epithelial cells and a few neuronal and muscle cells. A 1 h p...
Topics
- Animals
- Cell Transformation, Neoplastic
- Cells, Cultured
- Culture Media
- Embryo, Mammalian
- Inflammation
- Phenotype
- Phospholipid Ethers
- Platelet Activating Factor
- Platelet Membrane Glycoproteins
- Rats
- Rats, Sprague-Dawley
- Receptors, Cell Surface
- Receptors, G-Protein-Coupled