Article
Alpha-adducin Gly460Trp polymorphism and renal hemodynamics in essential hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Oct 2004
Beeks Esther, van der Klauw Melanie M, Kroon Abraham A, Spiering Wilko, Fuss-Lejeune Monique J M J, de Leeuw Peter W
Abstract excerpt
Previous studies have shown an association between the alpha-adducin Gly460Trp polymorphism and salt-sensitive hypertension. Not much is known about the effects of the variants of this polymorphism on renal hemodynamics and function. Therefore, we performed the present study to investigate the effect of the 460Trp allele of the alpha-adducin gene on renal hemodynamics in one hundred and seventeen essential...
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