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The alpha-adducin Gly460Trp polymorphism and the antihypertensive effects of exercise among men with high blood pressure.

Clinical science (London, England : 1979) - 1 Sept 2007

Pescatello Linda S, Blanchard Bruce E, Tsongalis Gregory J, Maresh Carl M, O'Connell Ann, Thompson Paul D

Abstract excerpt

The alpha-adducin Gly460Trp polymorphism alters renal sodium transport and is associated with hypertension. Despite the immediate sodium- and volume-depleting effects of aerobic exercise, the influence of the alpha-adducin Gly460Trp polymorphism on PEH (postexercise hypotension) has not been studied. In the present study we examined the effects of the alpha-adducin Gly460Trp polymorphism on PEH among 48 men...

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PMID: 17472579
DOI: 10.1042/CS20060345

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