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Article

Inhibition of cardiac HERG potassium channels by the atypical antidepressant trazodone.

Naunyn-Schmiedeberg's archives of pharmacology - 1 Aug 2004

Zitron Edgar, Kiesecker Claudia, Scholz Eberhard, Lück Sonja, Bloehs Ramona, Kathöfer Sven, Thomas Dierk, Kiehn Johann, Kreye Volker A W, Katus Hugo A, Schoels Wolfgang, Karle Christoph A

Abstract excerpt

Trazodone is an atypical antidepressant that is commonly used in the treatment of affective disorders. There have repeatedly been reports of cardiac arrhythmia associated with this drug and concerns have been raised regarding the cardiac safety of trazodone. However, interaction with HERG channel...

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Source

Identifiers

PMID: 15322737
DOI: 10.1007/s00210-004-0952-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15322737-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Inhibition of cardiac HERG potassium channels by the atypical antidepressant trazodone.PMID 15322737Read ↗

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