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Article

The rs150311303 polymorphism in FcγRIIa enhances IgG binding capacity.

Scandinavian journal of immunology - 1 Aug 2012

Omar A H, Shibata H, Yasunami M, Yamazaki A, Ofori M F, Akanmori B D, Shuaibu M N, Kikuchi M, Hirayama K

Abstract excerpt

Fc gamma receptor (FcγR) provides an important link between humoral and cellular immune responses. FcγRIIa-H131R polymorphism has been associated with differential binding to IgG subclasses and susceptibility to severe malaria phenotypes among different populations in the malaria endemic world. In this study, the effect of FCGR2A gene polymorphisms on susceptibility to symptomatic malaria among Ghanaian cohort...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22540264
DOI: 10.1111/j.1365-3083.2012.02715.x

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