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Article

Association between immunoglobulin GM and KM genotypes and placental malaria in HIV-1 negative and positive women in western Kenya.

PloS one - 1 Jan 2013

Iriemenam Nnaemeka C, Pandey Janardan P, Williamson John, Blackstock Anna J, Yesupriya Ajay, Namboodiri Aryan M, Rocca Keith M, van Eijk Anna Maria, Ayisi John, Oteino Juliana, Lal Renu B, ter Kuile Feiko O, Steketee Richard, Nahlen Bernard, Slutsker Laurence, Shi Ya Ping

Abstract excerpt

Immunoglobulin (Ig) GM and KM allotypes, genetic markers of γ and κ chains, are associated with humoral immune responsiveness. Previous studies have shown the relationships between GM6-carrying haplotypes and susceptibility to malaria infection in children and adults; however, the role of the genetic markers in placental malaria (PM) infection and PM with HIV co-infection during pregnancy has not been...

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Identifiers

PMID: 23326546
DOI: 10.1371/journal.pone.0053948
PMCID: PMC3543394

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