Article
Syntaxin 1A regulation of weakly inactivating N-type Ca2+ channels.
The Journal of physiology - 15 Oct 2004
Hurley Joyce H, Cahill Anne L, Wang Meijing, Fox Aaron P
Abstract excerpt
N- and P/Q-type Ca2+ channels are abundant in nerve terminals where they interact with proteins of the release apparatus, including syntaxin 1A and SNAP-25. In previous studies on N- or P/Q-type Ca2+ channels, syntaxin 1A co-expression reduced current amplitudes, increased voltage-dependent inactivation and/or enhanced G-protein inhibition. However, these studies were conducted in Ca2+ channels that exhibited...
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