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Article

Chromosomal instability and lack of cyclin E regulation in hCdc4 mutant human breast cancer cells.

Breast cancer research : BCR - 1 Jan 2004

Willmarth Nicole E, Albertson Donna G, Ethier Stephen P

Abstract excerpt

INTRODUCTION: Cyclin E, a G1 cyclin essential for G1-S phase transition, is known to have a profound effect on tumorigenesis. Elevated levels of cyclin E have been associated with breast cancer, and chromosomal instability observed in breast cancer is suggested to be associated with constitutive...

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Identifiers

PMID: 15318934
DOI: 10.1186/bcr900
PMCID: PMC549168

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15318934-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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