Article
A role for the transcription intermediary factor 2 in zebrafish myelopoiesis.
Experimental hematology - 1 May 2008
Zhuravleva Julia, Solary Eric, Chluba Johanna, Bastie Jean-Noël, Delva Laurent
Abstract excerpt
OBJECTIVE: TIF2 is fused with MOZ in the inv(8)(p11q13) acute myeloid leukemia. TIF2, member of the p160 family, is a histone acetyl transferase (HAT). Deletion of p160 genes were performed in mice. Some observations suggest that p160 family members may perform overlapping functions in mice. Therefore, we decided to choose the zebrafish model to study TIF2. The aim of this study was to characterize the role of...
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