Article
Blockade of transgenic gamma delta T cell development in beta 2-microglobulin deficient mice.
The EMBO journal - 1 Jan 1992
Pereira P, Zijlstra M, McMaster J, Loring J M, Jaenisch R, Tonegawa S
Abstract excerpt
The gamma delta T cell receptor (TCR) of the hybridoma KN6 recognizes the self molecule encoded by a class I gene which maps within the TL region of the major histocompatibility complex (MHC) of H-2b mice. Mice transgenic (Tg) for this TCR were crossed with mice genetically deficient in beta 2-mi...
Topics
- Animals
- Animals, Genetically Modified
- Antibodies, Monoclonal
- Antigens, CD
- Antigens, Differentiation
- Base Sequence
- CD24 Antigen
- Cell Differentiation
- Crosses, Genetic
- Embryo, Mammalian
- Gene Expression
- Genotype
- Haplotypes
- Immunohistochemistry
- Membrane Glycoproteins
- Mice
- Mice, Inbred Strains
- Molecular Sequence Data