Article
[Androgen function on skeletal tissues: analysis of androgen receptor-deficient mice].
Clinical calcium - 1 Mar 2006
Kawano Hirotaka, Kawaguchi Hiroshi
Abstract excerpt
Although sex hormones had been thought to be essential for normal skeletal development and maintenance of bone mass, the physiological role of androgen receptor (AR) in skeletal tissues was not well established. To reveal physiological function of AR on skeletal tissues, we generated AR deficient mice (AR KO) by means of the Cre-loxP system that was used to avoid the problem of male infertility and analyzed their...
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