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Article

Coregulator Recruitment and Histone Modifications in Transcriptional Regulation by the Androgen Receptor

13 Aug 2004

Abstract excerpt

We have used chromatin immunoprecipitation (ChIP) assay to follow transcription factor loading and monitor changes in covalent histone modifications associated with the prostate-specific antigen and kallikrein (KLK2) genes in response to androgen and antiandrogen in LNCaP cells. The dynamics of testosterone (T)-induced loading of androgen receptor (AR) onto the proximal promoters of the genes differed...

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Identifiers

PMID: 15308689
DOI: 10.1210/me.2004-0245

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