Article
Research Resource: Androgen Receptor Activity Is Regulated Through the Mobilization of Cell Surface Receptor Networks.
Molecular endocrinology (Baltimore, Md.) - 1 Aug 2015
Hsiao Jordy J, Ng Brandon H, Smits Melinda M, Martinez Harryl D, Jasavala Rohini J, Hinkson Izumi V, Fermin Damian, Eng Jimmy K, Nesvizhskii Alexey I, Wright Michael E
Abstract excerpt
The aberrant expression of androgen receptor (AR)-dependent transcriptional programs is a defining pathology of the development and progression of prostate cancers. Transcriptional cofactors that bind AR are critical determinants of prostate tumorigenesis. To gain a deeper understanding of the proteins linked to AR-dependent gene transcription, we performed a DNA-affinity chromatography-based proteomic screen...
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