Article

Androgen receptor-mediated assisted loading of the glucocorticoid receptor modulates transcriptional responses in prostate cancer cells

2024-11-15

Abstract excerpt

<h4>ABSTRACT</h4> Steroid receptors are involved in a wide array of crosstalk mechanisms that regulate diverse biological processes, with significant implications in diseases, particularly in cancers. In prostate cancer, indirect crosstalk between androgen receptor (AR) and glucocorticoid receptor (GR) is well-documented, wherein AR suppression by antiandrogen therapy leads to elevated GR levels, enabling GR to c...

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Literature Corpus work: 399ca4b7-feb5-50db-bddb-994f1de92a08
DOI: 10.1101/2024.11.15.623719

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