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The epigenetic function of androgen receptor in prostate cancer progression

21 Mar 2023

Abstract excerpt

Androgen and androgen deprivation (castration) therapies, including androgen receptor antagonists, are clinically used to treat patients with prostate cancer. However, most hormone-dependent prostate cancer patients progress into a malignant state with loss of hormone-dependency, known as castration (drug)-resistant prostate cancer (CRPC), after prolong androgen-based treatments. Even in the CRPC state with...

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PMID: 37025180
DOI: 10.3389/fcell.2023.1083486

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