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Article

Cell type-specific regulation of RhoA activity during cytokinesis.

The Journal of biological chemistry - 22 Oct 2004

Yoshizaki Hisayoshi, Ohba Yusuke, Parrini Maria-Carla, Dulyaninova Natalya G, Bresnick Anne R, Mochizuki Naoki, Matsuda Michiyuki

Abstract excerpt

Rho family GTPases play pivotal roles in cytokinesis. By using probes based on the principle of fluorescence resonance energy transfer (FRET), we have shown that in HeLa cells RhoA activity increases with the progression of cytokinesis. Here we show that in Rat1A cells RhoA activity remained suppressed during most of the cytokinesis. Consistent with this observation, the expression of C3 toxin inhibited...

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PMID: 15308673
DOI: 10.1074/jbc.M402292200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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