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Article

A systems biology approach sheds new light on Escherichia coli acid resistance.

Nucleic acids research - 1 Sept 2011

Stincone Anna, Daudi Nazish, Rahman Ayesha S, Antczak Philipp, Henderson Ian, Cole Jeffrey, Johnson Matthew D, Lund Peter, Falciani Francesco

Abstract excerpt

In order to develop an infection, diarrhogenic Escherichia coli has to pass through the stomach, where the pH can be as low as 1. Mechanisms that enable E. coli to survive in low pH are thus potentially relevant for pathogenicity. Four acid response systems involved in reducing the concentration of intracellular protons have been identified so far. However, it is still unclear to what extent the regulation of...

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Identifiers

PMID: 21690099
DOI: 10.1093/nar/gkr338
PMCID: PMC3177180

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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