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Article

The PhoP-PhoQ two-component regulatory system of Photorhabdus luminescens is essential for virulence in insects.

Journal of bacteriology - 1 Mar 2004

Derzelle Sylviane, Turlin Evelyne, Duchaud Eric, Pages Sylvie, Kunst Frank, Givaudan Alain, Danchin Antoine

Abstract excerpt

Photorhabdus luminescens is a symbiont of entomopathogenic nematodes. Analysis of the genome sequence of this organism revealed a homologue of PhoP-PhoQ, a two-component system associated with virulence in intracellular bacterial pathogens. This organism was shown to respond to the availability of environmental magnesium. A mutant with a knockout mutation in the regulatory component of this system (phoP) had no...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 14973084
DOI: 10.1128/JB.186.5.1270-1279.2004
PMCID: PMC344422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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