Article
[A case-control study on the polymorphisms of methylenetetrahydrofolate reductases, drinking interaction and susceptibility in colorectal cancer].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 1 Jul 2004
Jiang Qin-ting, Chen Kun, Ma Xin-yuan, Miao Xiao-ping, Yao Kai-yan, Yu Wei-ping, Li Ling-yun, Zhu Yi-min, Zhou Hai-guang
Abstract excerpt
OBJECTIVE: To investigate the relationship between methylenetetrahydrofolate reductases (MTHFR) polymorphisms and colorectal cancer susceptibility. METHODS: A case-control study of 126 patients and 343 healthy controls was conducted to investigate the roles of MTHFR C677T and A1298C polymorphisms in colorectal cancer development. Genotypes of C677T and A1298C polymorphisms were analyzed by polymerase chain...
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