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Article

[Association between genetic variations in methylenetetrahydrofolate reductase and risk of colorectal cancer in a Chinese population].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 Nov 2005

Miao Xiao-ping, Yang Shen, Tan Wen, Zhang Xue-mei, Ye Ying-jiang, Lin Dong-xin, Wang Shan

Abstract excerpt

OBJECTIVE: To investigate the association between genetic variations in methylenetetrahydrofolate reductase (MTHFR) and the risk of colorectal cancer in a Chinese population. METHODS: One hundred and ninety-eight cases of colorectal cancer and 420 controls were genotyped for detecting MTHFR C677T and A1298C polymorphisms by PCR-RFLP methods. The adjusted odds ratios (OR) and 95% confidence intervals (CI) were...

Topics

Asian People
China
Colorectal Neoplasms
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
Logistic Models
Methylenetetrahydrofolate Reductase (NADPH2)
Odds Ratio

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Polymorphism, Single Nucleotide

Risk Factors

Source

Identifiers

PMID: 16329804

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-16329804-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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