Article
Frequency of the mutant MDR1 allele associated with multidrug sensitivity in a sample of collies from France.
Journal of veterinary pharmacology and therapeutics - 1 Aug 2004
Hugnet C, Bentjen S A, Mealey K L
Abstract excerpt
A study was performed to determine the frequency of the mutant MDR1 allele associated with ivermectin sensitivity in a sample of collies living in France. Buccal swab samples were collected from approximately 83 collies for determination of MDR1 genotype. DNA was extracted and the polymerase chain reaction was performed to amplify a 148 bp (wildtype MDR1 genotype) or 144 bp (mutant MDR1 genotype) amplicon...
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