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Article

Flagellin-dependent and -independent inflammatory responses following infection by enteropathogenic Escherichia coli and Citrobacter rodentium.

Infection and immunity - 1 Apr 2008

Khan Mohammed A, Bouzari Saeid, Ma Caixia, Rosenberger Carrie M, Bergstrom Kirk S B, Gibson Deanna L, Steiner Theodore S, Vallance Bruce A

Abstract excerpt

Enteropathogenic Escherichia coli (EPEC) and the murine pathogen Citrobacter rodentium belong to the attaching and effacing (A/E) family of bacterial pathogens. These noninvasive bacteria infect intestinal enterocytes using a type 3 secretion system (T3SS), leading to diarrheal disease and intestinal inflammation. While flagellin, the secreted product of the EPEC fliC gene, causes the release of interleukin 8...

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Identifiers

PMID: 18227166
DOI: 10.1128/IAI.01141-07
PMCID: PMC2292885

Genes

TLR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Flagellin-dependent and -independent inflammatory responses following infection by enteropathogenic Escherichia coli and Citrobacter rodentium.PMID 18227166Read ↗

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