Article
Novel single nucleotide polymorphisms in the human immune inhibitory immunoglobulin-like T cell receptor type 4.
Human immunology - 1 Jul 2004
Papanikolaou Nikolaos A, Vasilescu Elena R, Suciu-Foca Nicole
Abstract excerpt
The capacity of antigen presenting cells to induce anergy in T helper cells and elicit the generation of T suppressor cells is regulated by a variety of positive and negative signals. Antigen-specific CD8(+)CD28(-) and CD4(+)CD25(+) T suppressor/regulatory cells induce the upregulation of inhibitory receptors expressed by antigen-presenting cells (APC) belonging to the family of immunoglobulin-like transcripts...
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