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Article

Xantivin suppresses the activity of EGF-CFC genes to regulate nodal signaling.

The International journal of developmental biology - 1 Jun 2004

Tanegashima Kousuke, Haramoto Yoshikazu, Yokota Chika, Takahashi Shuji, Asashima Makoto

Abstract excerpt

Lefty, antivin and related genes act in a feedback inhibition mechanism for nodal signaling at a number of stages of vertebrate embryogenesis. To analyze the function of the feedback inhibitor of nodal signaling, Xantivin in Xenopus embryos, we designed a morpholino antisense oligonucleotide (XatvMO) for this gene. XatvMO caused the expansion of mesodermal tissue and head defects. XatvMO-injected gastrulae showed...

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Source

Identifiers

PMID: 15300508
DOI: 10.1387/ijdb.041805kt

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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