Antivin, a novel and divergent member of the TGFbeta superfamily, negatively regulates mesoderm induction.

doi:10.1242/dev.126.2.229

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Antivin, a novel and divergent member of the TGFbeta superfamily, negatively regulates mesoderm induction.

Development (Cambridge, England) - 1 Jan 1999

Thisse C, Thisse B

Abstract excerpt

Mesoderm induction and patterning are mediated by members of the TGFbeta superfamily. We have isolated a novel zebrafish member, antivin, that structurally is highly related to mouse lefty. Overexpression of antivin completely abolishes mesoderm induction at blastula stage, yet resultant embryos...

Topics

Activin Receptors
Activins
Amino Acid Sequence
Animals
Blastocyst
Body Patterning
Cell Differentiation
Embryo, Nonmammalian
Gene Expression Regulation, Developmental
In Situ Hybridization
Inhibins
Left-Right Determination Factors
Mesoderm
Molecular Sequence Data
Phenotype
RNA, Messenger
Receptors, Growth Factor
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 9847237
DOI: 10.1242/dev.126.2.229

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9847237-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics