Article
Seasonality in clinical onset of type 1 diabetes in belgian patients above the age of 10 is restricted to HLA-DQ2/DQ8-negative males, which explains the male to female excess in incidence.
Diabetologia - 1 Apr 2004
Weets I, Kaufman L, Van der Auwera B, Crenier L, Rooman R P A, De Block C, Casteels K, Weber E, Coeckelberghs M, Laron Z, Pipeleers D G, Gorus F K
Abstract excerpt
AIMS/HYPOTHESIS: Type 1 diabetes arises from an interplay between environmental and genetic factors. The reported seasonality at diagnosis supports the hypothesis that currently unknown external triggers play a role in the onset of the disease. We investigated whether a seasonal pattern is observed at diagnosis in Belgian Type 1 diabetic patients, and if so whether seasonality varies according to age, sex and...
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