Article
Relative and absolute HLA-DQA1-DQB1 linked risk for developing type I diabetes before 40 years of age in the Belgian population: implications for future prevention studies.
Human immunology - 1 Jan 2002
Van der Auwera Bart J, Schuit Frans C, Weets Ilse, Ivens Ann, Van Autreve Jan E, Gorus Frans K
Abstract excerpt
HLA-DQ genotyping remains the cornerstone of genetic risk stratification in type I diabetes prediction and prevention studies. We developed a genetic screening strategy for predisposition to type I diabetes in the Belgian population based upon HLA-DQA1-DQB1 typing and taking into account the age at clinical onset. A group of 1866 autoantibody-positive type I patients below age 40 years recruited by the Belgian...
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