Article
HLA-DR genotypes influence age at disease onset in children and juveniles with type 1 diabetes mellitus.
European journal of endocrinology - 1 Jul 2010
Awa W L, Boehm B O, Kapellen T, Rami B, Rupprath P, Marg W, Becker M, Holl R W
Abstract excerpt
OBJECTIVE: To investigate HLA-DR genotype in association with chronological age or calendar year of disease onset and the time trend of genotype frequencies from 1969 to 2009. Additionally, to examine genotype frequency in relation to B-cell-, islet cell antibodies (ICA)-, autoantibodies to insulin-, insulinoma antigen 2 (IA2)-, glutamic acid decarboxylase-antibody positivity, thyroid antibody positivity, thyroid...
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