Article
Associations between IL12B polymorphisms and tuberculosis in the Hong Kong Chinese population.
The Journal of infectious diseases - 1 Sept 2004
Tso Hoi W, Lau Yu Lung, Tam Cheuk M, Wong Hing S, Chiang Alan K S
Abstract excerpt
BACKGROUND: Interleukin (IL)-12 plays a vital role in regulating cell-mediated immunity against tuberculosis (TB). METHODS: To test whether IL12B genetic polymorphisms might contribute to human TB susceptibility, we examined the genotype frequencies of 5 IL12B polymorphisms (at promoter, intron 2, intron 4, exon 5, and 3' untranslated region [UTR]) in 516 patients with TB and 514 healthy control subjects from the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
