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Association of gene polymorphisms and environmental factors in tuberculosis patients and their household contacts.

Transactions of the Royal Society of Tropical Medicine and Hygiene - 7 Jan 2021

Chen Yue, Peng Wen Hui, Lai Shi Feng, Luo Fang, Luo Dan, Wang Bao Guo

Abstract excerpt

BACKGROUND: Tuberculosis (TB) is an important public health problem in China and environmental and genetic factors have an impact on its occurrence and development. We explored the relationship between environmental factors, genetic susceptibility genes and gene-environment interactions and the incidence of TB, as well as their high-risk combination, which can provide a scientific basis for prevention of the...

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PMID: 32853361
DOI: 10.1093/trstmh/traa076

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