Article
Genetic association between a chemokine gene CXCL-10 (IP-10, interferon gamma inducible protein 10) and susceptibility to tuberculosis.
Clinica chimica acta; international journal of clinical chemistry - 1 Aug 2009
Tang Nelson Leung-Sang, Fan Harris Pok Yin, Chang Kwok Chiu, Ching Jasmine Kuk Lai, Kong Kathy Pui Shan, Yew Wing Wai, Kam Kai Man, Leung Chi Chiu, Tam Cheuk Ming, Blackwell Jenefer, Chan Chiu Yeung
Abstract excerpt
BACKGROUND: Previous studies showed that activation of CXCL-10 and other chemokines were prominent in many infectious diseases. These chemokines are components of innate immune response to respiratory tract pathogens. We examined the promoter variants of CXCL-10 and their role in predisposition to tuberculosis (TB). METHODS: The promoter 1.8 kb of CXCL-10 was sequenced in 24 healthy Chinese individuals to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
