Article
Evidence for the multigenic inheritance of schizophrenia.
American journal of medical genetics - 8 Dec 2001
Freedman R, Leonard S, Olincy A, Kaufmann C A, Malaspina D, Cloninger C R, Svrakic D, Faraone S V, Tsuang M T
Abstract excerpt
Schizophrenia is assumed to have complex inheritance because of its high prevalence and sporadic familial transmission. Findings of linkage on different chromosomes in various studies corroborate this assumption. It is not known whether these findings represent heterogeneous inheritance, in which various ethnic groups inherit illness through different major gene effects, or multigenic inheritance, in which...
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