Article
No evidence for linkage between schizophrenia and markers at chromosome 15q13-14.
American journal of medical genetics - 16 Apr 1999
Curtis L, Blouin J L, Radhakrishna U, Gehrig C, Lasseter V K, Wolyniec P, Nestadt G, Dombroski B, Kazazian H H, Pulver A E, Housman D, Bertrand D, Antonarakis S E
Abstract excerpt
Freedman et al. [1997: Proc Natl Acad Sci USA 94:587-592] reported linkage in nine multiplex schizophrenia families to markers on chromosome 15, using impaired neuronal inhibition to repeated auditory stimuli (P50), a neurophysiological deficit associated with schizophrenia, as the phenotype. The highest LOD score obtained (5.3 at theta = 0) was for marker D15S1360 mapped to chromosome 15q13-14, less than 120 kb...
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