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Article

The Val103Ile polymorphism of melanocortin-4 receptor regulates energy expenditure and weight gain.

Obesity research - 1 Jul 2004

Rutanen Jarno, Pihlajamäki Jussi, Karhapää Pauli, Vauhkonen Ilkka, Kuusisto Johanna, Moilanen Mykkänen Leena, Laakso Markku

Abstract excerpt

OBJECTIVE: The melanocortin-4 receptor (MC4R) regulates energy intake. On the basis of animal studies, it may also regulate energy expenditure. RESEARCH METHODS AND PROCEDURES: The effect of the Val103Ile polymorphism of the MC4R gene on energy metabolism was studied in 229 middle-aged nondiabetic subjects (Group 1, age 51.2 +/- 9.8 years, BMI 26.8 +/- 4.5 kg/m2) and on weight gain in 1013 elderly subjects (Group...

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Source

Identifiers

PMID: 15292469
DOI: 10.1038/oby.2004.133

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Val103Ile polymorphism of melanocortin-4 receptor regulates energy expenditure and weight gain.PMID 15292469Read ↗

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